Aldol Addition / Aldol Reaction
Aldol Addition Reaction |
Mechanism of Aldol Reaction
Aldol Reaction Mechanism - Acid Catalyzed and Base Catalyzed |
If we control kinetic condition for aldol reactions then mixed aldol addition reactions may be used for the preparation of the adducts that can not be obtain selectively.
This method begins
with irreversible production of kinetic
enolate, for example by employ the sterically or delayed lithium-amide-base like
LDA known as lithiumdiisopropylamide and abbreviated as LDA.